Author’s response to reviews Title: Is there an added value of faecal calprotectin and haemoglobin in the diagnostic work-up for primary care patients suspected of significant colorectal disease? A cross-sectional diagnostic study Authors:
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چکیده
Title: Is there an added value of faecal calprotectin and haemoglobin in the diagnostic work-up for primary care patients suspected of significant colorectal disease? A cross-sectional diagnostic study Authors: Sjoerd Elias ([email protected]) Liselotte Kok ([email protected]) Niek de Wit ([email protected]) Ben Witteman ([email protected]) Jelle Goedhard ([email protected]) Mariëlle Romberg-Camps ([email protected]) Jean Muris ([email protected]) Karel Moons ([email protected]) Version: 1 Date: 02 Aug 2016 Author’s response to reviews: Reviewer 1
منابع مشابه
Is there an added value of faecal calprotectin and haemoglobin in the diagnostic work-up for primary care patients suspected of significant colorectal disease? A cross-sectional diagnostic study
BACKGROUND The majority of primary care patients referred for bowel endoscopy do not have significant colorectal disease (SCD), and are - in hindsight - unnecessarily exposed to a small but realistic risk of severe endoscopy-associated complications. We developed a diagnostic strategy to better exclude SCD in these patients and evaluated the value of adding a faecal calprotectin point-of-care (...
متن کاملErratum to: Diagnostic work-up of patients presenting in primary care with lower abdominal symptoms: which faecal test and triage strategy should be used?
Bowel endoscopy referrals from primary care have increased steadily over recent years. However, most patients do not have significant colorectal disease (SCD). Therefore, strategies to select those who would benefit most from endoscopy are of current interest. A recent study developed a multivariable diagnostic model for SCD with routine clinical information, extended with quantitative faecal c...
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OBJECTIVE In primary care, assessing which patients with bowel symptoms harbour significant disease (cancer, higher-risk adenoma or IBD) is difficult. We studied the diagnostic accuracies of faecal haemoglobin (FHb) and faecal calprotectin (FC) in a cohort of symptomatic patients. DESIGN From October 2013 to March 2014, general practitioners were prompted to request FHb and FC when referring ...
متن کاملClinical Relevance of Faecal Calprotectin Level in Infantile Colic: A Cross-sectional Survey
Background: There is limited knowledge on the potential applicability of fecal calprotectin (f-CP) as an inflammatory screening parameter in infantile colic (IC). This study aimed to evaluate f-CP in neonates with IC as a useful diagnostic indicator regarding this condition. Methods: The present study was conducted on 100 cases, including 50 newborns with IC and 50 non-colicky neonates. The dia...
متن کاملFaecal calprotectin in patients with suspected colorectal cancer: a diagnostic accuracy study.
BACKGROUND NICE guidance exists for the use of faecal calprotectin (FC) when irritable bowel syndrome or inflammatory bowel disease are suspected. Often, however, colorectal cancer is considered within the differential. Should FC have a high diagnostic accuracy for colorectal cancer, it may be applicable as a primary care screening test for all patients with lower gastrointestinal symptoms. A...
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